AI Solutions Portfolio Manager

Do you have strong organizational skills, a proactive mindset and the passion for pushing assignments through to execution? Would you like to use your experience to support a company that turns ideas into life changing medicines? Then AstraZeneca might be the one for you!  

At AstraZeneca every one of our employees makes a difference to patient lives every day. Each and every one of us believes that science has the ability to change lives and that to deliver this takes many people with many skill sets. When we deliver a life-changing medicine, that success comes from the combined efforts of all of our people.  

Position Summary

Partner closely with the AI to Transform Care (AITC) Strategy & Ops Lead to build and maintain a structured, transparent, and strategically aligned AI solutions portfolio - ensuring AITC projects are clearly defined, managed, and tracked – delivering measurable impact to patients, healthcare professional and healthcare systems. As the AITC team manage multiple high-priority initiatives, this role will serve as a critical link between strategy and execution, ensuring that the overall portfolio remains coherent, aligned, and deliverable in practice. 

Beyond portfolio oversight and reporting, the role holder is also expected to support selected flagship AITC solutions – serving as an internal accelerator to remove barriers, sharpen narratives, and drive delivery momentum where required. 

Responsibilities 

• Portfolio Architecture & Oversight: Own and continuously refine a comprehensive, up-to-date overview of all AI solutions developed and deployed across AITC. Ensure initiatives are clearly scoped, defined, and mapped to AITC's strategic priorities and AI30 objectives – maintaining a single source of truth for the portfolio that leadership can rely on for decision-making. 

• Strategic Prioritization & Investment Decisions: Support the AITC LT in prioritizing initiatives across the portfolio – balancing strategic value with resource availability and ability to deliver. Provide structured analysis and recommendations to inform go/no-go decisions, resource allocation, and sequencing of programs. 

• Performance & Impact Measurement: Work closely with program leads to define and track benefits realization plans for each AI solution – ensuring that expected clinical, operational, and commercial outcomes are clearly articulated, measured, and reported. Connect portfolio outcomes to AITC's KPI framework and AI30 scorecard metrics. 

• Governance & Portfolio Reviews: Design and run the AITC portfolio governance process, including regular portfolio review forums with the LT. Prepare portfolio-level materials for internal governance, EAI LT engagement, and strategic planning cycles. Ensure decision-making across the portfolio is structured, consistent, and well-documented. 

• Interdependency & Risk Management: Proactively identify and manage interdependencies, resource conflicts, and delivery risks across the portfolio. Work with program leads and functional partners to resolve issues before they affect delivery timelines or strategic commitments. 

• Stakeholder Communication: Serve as the primary point of contact for portfolio-level visibility across AITC – synthesizing complex, multi-program information into clear, accessible updates for the LT, EAI leadership, and cross-functional partners. Translate portfolio data into strategic narratives that reinforce AITC's value and progress. 

•  Strategic Solutions Support: Act as an embedded strategic partner to project leads driving high-priority AITC solutions — helping to unblock barriers, sharpen project narratives, coordinate cross-functional inputs, and drive momentum where external visibility or internal alignment is needed. 

Essential requirements 

The ideal candidate combines project management expertise with the ability to operate effectively in a dynamic, fast-paced, and evolving environment, alongside a genuine understanding of AI and data-driven solutions in a complex, matrixed organization: 

• Experience building structure and governance across a portfolio, ensuring initiatives are clearly scoped, prioritized, tracked, and aligned to strategic objectives. 

• Proven ability to manage multiple initiatives or workstreams simultaneously, with strong organizational discipline and attention to detail. 

• Excellent analytical and problem-solving skills, with a focus on execution and outcomes. 

• Strong communication skills – able to synthesize complex information into clear, concise, executive-ready materials for senior stakeholders. 

• Strong stakeholder management and interpersonal skills – able to build trusted relationships across diverse, cross-functional, and international teams. 

• Good understanding of AI, data-driven solutions, or digital innovation, with the ability to engage credibly with project leads and leadership. 

• High level of ownership, proactivity, and commitment to delivery excellence. 

Desirable qualifications 

• Experience in AI, digital health, or data-driven transformation programs. 

• Background in portfolio governance, prioritization, benefits tracking, or KPI reporting. 

• Experience working in the pharmaceutical, biotech, healthcare, or life sciences industry. 

• Familiarity with strategic planning cycles, investment decisions, or business case development. 

• Experience supporting senior leadership teams in a complex, matrixed, international organization. 

• Strong capability with Microsoft 365, especially PowerPoint, Excel, Teams, and SharePoint as well as collaboration and reporting tools. 

• Additional languages, especially Spanish, French, and/or German are an advantage. 

Why AstraZeneca?