Director, Product Communications

Definium Therapeutics · Durham, North Carolina, United States

Definium Therapeutics is a late-stage clinical biopharmaceutical and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.  

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.     

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX. 

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

We are seeking a seasoned, dynamic Director, Product Communications to lead strategic communications for the company’s late-stage pipeline, including Phase 3 data readouts, potential regulatory filings, and future launch readiness. This role will be central to shaping the external and internal narrative around Definium’s scientific rigor and innovation, stewarding corporate and product reputation through critical clinical milestones, and helping prepare the market for a potential first-in-class launch.

This individual will report into the VP of Corporate Communications, and will work in close partnership with Commercial, Medical Affairs, Investor Relations, Human Resources, Patient Advocacy, Government Affairs, and other cross-functional leaders to develop clear, compliant, and high-impact messaging and programming across earned, owned, social/digital, and shared channels. The goal is to ensure Definium’s story is communicated with consistency, credibility, and relevance to key stakeholders, including employees, patients, healthcare providers, investors, and payers. 

The ideal candidate is an experienced communications professional with deep pharmaceutical experience who can operate strategically and execute flawlessly in a fast-paced, high-visibility, environment.

Responsibilities:

  • Lead the development and execution of integrated communications programs that elevate awareness of product differentiation and their potential to address unmet medical needs in support of company goals.
  • Serve as the communications lead for our commercial product teams and participate in regular team planning meetings
  • Establish collaborative working relationships with R&D, medical affairs, regulatory, government affairs, and brand teams to develop communications plans that shape differentiated messaging across audiences that redefine a new era in psychedelics and psychiatric care
  • Direct multiplatform, integrated PESO (paid, earned, social, owned) communications campaigns
  • Develop and deploy media relations plans; work with and maintain relationships with journalists
  • Reflecting the increasingly social/digital way that key audiences get their information, a predominant focus will be on the strategic design and implementation of sophisticated, highly targeted social/digital efforts designed to educate, raise awareness, and shape the market ahead of potential launch
  • Support KPI and measurement framework development, and provide regular readouts/metrics tracking with recommendations for optimization
  • Lead reputation and issues preparedness planning, including scenario planning, Q&A development, and leadership briefings
  • Partner with Medical Affairs and Clinical Development to ensure accurate translation of complex scientific information into clear, compliant, targeted communications
  • Develop engaging employee communications that inform, align, and excite colleagues about our pipeline and products
  • Oversee materials through Definium’s internal review systems, ensuring all content meets regulatory, legal, and business standards
  • Represent function on integrated teams and proactively contribute to decision-making with business partners
  • Manage PR agency, ensuring alignment between internal decisions and agency work product, while ensuring delivery of high-quality, strategically aligned work on time and on budget
  • Help ensure Definium remains on the cutting edge by incorporating the latest technology (e.g., AI) and data into planning and measurement efforts

Qualifications:

  • Bachelor’s degree with a minimum of 10 years in the pharmaceutical or biotech industry, with experience in product communications, ideally with CNS, psychiatry, or neurology experience
  • Significant experience in clinical data communications, with a proven ability to synthesize complex data into actionable strategies and work across functions to secure alignment and approvals
  • Previous in-house and agency experience
  • Strong understanding of the US healthcare landscape, including regulatory policy and market access, and the fast-paced media environment across earned and digital/social platforms
  • Willingness to set strategy and long-range plans while driving outcomes in a hands-on manner
  • Strong executive presence with demonstrated experience advising senior leaders
  • Excellent written, verbal, and interpersonal communication skills
  • Experience managing agencies, budgets, and cross‑functional alignment
  • Flexibility and agility to navigate dynamic, fast-paced environments; ability to adapt with evolving business needs
  • Collaborative team player with an enterprise mindset who can work effectively in cross-functional teams
  • Independently motivated, detail-oriented, and good problem-solving ability
  • Up to 20% of travel may be required based upon business needs

The starting base pay range for this position is $192,904.00 - $226,600.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.

Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:

  • 100% paid health benefits including Medical, Dental and Vision for you and your dependents
  • 401(k) program with company match and vesting after the turn of the first month after your start date
  • Flexible time off
  • Generous parental leave and some fun fringe perks!

 

 

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