Sr. Scientist, Analytical R&D

Job Description

The Discovery Analytical Research group within Analytical Enabling Capabilities is seeking applicants for a Senior Scientist position available at Boston, Massachusetts research facility. The successful candidate will contribute to the efforts in enabling the discovery of new drug candidates including biologics, small molecules and other emerging modalities. Key deliverables will include the development, implementation, and execution of analytical measurement technologies that may accelerate the pace of discovery research and influence molecular design. The successful candidate must be able to collaborate in a dynamic, integrated, and multidisciplinary team environment. A broad range of tools (e.g. high-resolution mass spectrometry, chromatography, spectroscopy…etc.) are leveraged and new technologies are developed to influence selection of new drug candidates and enhance scalability and robustness.

The ideal candidate will have knowledge and proficiency in the following areas: high resolution mass spectrometry and separation techniques. Strong fundamental knowledge in recent advances in analytical technologies is highly desired. Applicants must have effective organizational skills, multi-tasking, oral / written communications skills, scientific leadership and a desire to conduct research and publish in peer-reviewed scientific journals.

Primary Responsibilities:

• Enable discovery partner groups with advanced analytical methods

• Represent the discovery analytical research group in project teams.

• Solve challenging problems by application of one or more analytical technique, including but not limited to, high-resolution mass spectrometry, liquid chromatography, capillary electrophoresis, ion chromatography, size exclusion chromatography, and two-dimensional techniques.

• Explore and develop new technologies applicable to the field of measurement science.

• Demonstrate effective multitasking, prioritization and problem-solving skills in the planning and execution of experiments.

• The successful candidate must be able to effectively collaborate in a fast-paced, integrated, multidisciplinary team environment.

Education Minimum Requirements:

• Ph.D. in Analytical Chemistry or related field / or

• MS in Analytical Chemistry or related field with 5+ years of biopharmaceutical industry experience.

Required Experience and Skills:

• Strong background and extensive hands-on experience in high-resolution mass spectrometry of large molecules (Proteins, mAb, ADC…etc) and separation science techniques.

• Demonstrated scientific ability through publications in peer reviewed journals and presentations in scientific conferences.

• Excellent verbal and written communication skills, demonstrated creativity, and strong interpersonal skills.

• Ability to deliver complex objectives under challenging timelines in a rapidly changing environment.

• Ability to work in a team environment with cross-functional interactions.

Preferred Experience and Skills:

• Understanding of biochemistry and organic chemistry.

• Familiarity with electronic laboratory notebook applications and good documentation practices.

Required Skills:

Analytical Chemistry, Analytical Method Development, Assay Development, Bioanalytical Analysis, Biochemical Assays, Biopharmaceuticals, Cell-Based Assays, Chromatographic Techniques, Chromatography, GMP Environments, Liquid Chromatography-Mass Spectrometry (LC-MS), Mass Spectrometry (MS), Nuclear Magnetic Resonance (NMR) Analysis, Process Analytical Technology (PAT), Ultra Performance Liquid Chromatography (UPLC)

Preferred Skills:

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Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

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As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

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The salary range for this role is

$119,100.00 - $187,500.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

06/24/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.