Biostatistical Programming Senior Manager

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Biostatistical Programming Senior Manager based in United States.

This role sits at the intersection of advanced biostatistics, programming, and real-world evidence generation, supporting observational research within a dynamic clinical data environment.
You will lead a US-based programming team responsible for delivering high-quality analytical outputs for studies in the obesity therapeutic area.
The position plays a key role in designing, validating, and executing programming solutions that support regulatory submissions and scientific publications.
You will oversee project timelines, resource planning, and cross-functional collaboration across clinical research, data management, and statistical teams.
This is a leadership-heavy role combining technical depth in programming languages with strategic oversight of real-world data and analytics.
You will also help shape standards, processes, and automation initiatives that improve efficiency and quality across programming operations.
The environment is highly collaborative, science-driven, and focused on impactful research that ultimately supports better patient outcomes.

• Lead, manage, and develop a team of statistical programmers supporting real-world evidence and observational research projects
• Oversee end-to-end programming activities including study planning, execution, timelines, and resource allocation
• Design, review, and approve programming plans, analysis datasets, and technical specifications
• Develop and validate programs, macros, and utilities to generate analysis-ready datasets and outputs in Unix-based environments
• Ensure compliance with internal standards, SOPs, regulatory requirements, and audit readiness across all deliverables
• Collaborate with cross-functional stakeholders including data management, clinical operations, and biostatistics teams
• Review vendor proposals and manage outsourced programming resources when applicable
• Contribute to process improvement, standardization, and automation initiatives within the programming function
• Support recruitment, training, and development of programming staff

Requirements:

• Bachelor’s degree with 6+ years, Master’s degree with 4+ years, or Doctorate with 2+ years of relevant experience (or equivalent combinations)
• At least 10 years of experience in clinical research, drug development, or statistical programming in a regulated environment
• Strong expertise in statistical programming languages, particularly SAS or similar procedural languages
• Solid understanding of real-world data sources such as claims and electronic medical records
• Experience with Unix systems and software development environments preferred
• Proven leadership experience managing technical teams and complex projects
• Strong background in project planning, process improvement, and cross-functional collaboration
• Knowledge of clinical drug development lifecycle and regulatory standards
• Ability to develop policies, SOPs, and controlled documentation in a research environment
• Strong communication, problem-solving, and stakeholder management skills

Benefits:

• Competitive annual salary range approximately 151,838.05 USD to 205,427.95 USD (based on experience and qualifications)
• Comprehensive health, dental, and vision insurance for employees and eligible dependents
• Retirement and savings plans with company contributions
• Annual discretionary bonus or performance-based incentive opportunities
• Stock-based long-term incentive programs
• Flexible work arrangements depending on role eligibility
• Generous paid time off and well-being-focused leave policies
• Career development opportunities in a global research and innovation environment